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Reglan injection iv or im ipenem) were tested in the primary prevention trial and secondary of the MDA for non-small cell lung cancer (NSCLC) [15] – [17]. The data of this meta-analysis include 12 trials including 6,736 patients aged 30 years and under who received MDA at any stage of Lung Cancer and received no chemotherapy prior to MDA or at any other time during the first or subsequent 5 years of their MDA. Patients in four trials were randomized to receive MDA or placebo, but two trials were generic adderall white pill excluded from the statistical analysis as placebo arm was not randomized. No significant differences between MDA and placebo could be demonstrated for the overall response rates when comparing MDA and placebo at all three time points buy placebo adderall pills (data not shown). We included two non-randomized trials that a smaller number of patients than the randomized trials. It should be noted that patients who completed four or more treatment years were excluded from the statistical analysis. All outcomes at baseline, and the end of four or more treatment years were included in the meta-analysis. studies examined included an overall response rate, the proportion of patients with a progression-free survival rate (PFS), and the median survival rates. Discussion The results of meta-analysis support that patients with advanced lung and non-small cell cancer are at an advantage over those without lung cancer in a long-term survival rate when given an IM injection of MDA. While we do not yet have information from other meta-analyses that directly compare the long-term survival rates of patients receiving IM MDA compared to control, the pooled summary estimate was significantly (p =.04) better in the IM treated patients compared to the control (Table III, Figure II). Furthermore, the pooled summary estimate of PFS (3.7 months vs 4.4 months) was statistically different than any one trial at either of the first three time points (Figure III). While some trial results suggested that the pooled PFS of 4.1 months was similar to that of 2.3 months in a non-randomized trial that focused solely on patients with a single tumor, it is noteworthy that this pooled PFS | ||||||